Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690333 | 0.83 | NUDT1 (0.35) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL15579070 | 0.81 | NUDT1 (0.43) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL8030891 | 0.75 | TRPV4 (0.30) | SMN1; SMN2 | |
| SCHEMBL7870509 | 0.71 | JAK1 (0.50) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL8113170 | 0.69 | TSHR (0.39) | TSHR | |
| SCHEMBL910274 | 0.67 | GAA (0.42) | GAATSHRSMN1; SMN2MAPK1 | |
| SCHEMBL7859414 | 0.67 | JAK2 (0.38) | JAK1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL31489196 | 0.67 | JAK1 (0.39) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL31489390 | 0.67 | JAK1 (0.39) | JAK1NUDT1KDM4EALDH1A1HPGD | |
| SCHEMBL4063510 | 0.63 | NUDT1 (0.38) | JAK1NUDT1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | disclosed |