Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | PAK4 | O96013 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489506 | 0.91 | ROCK2 (0.34) | MAPK1PIK3CGPDE10AROCK2KDM4E | |
| SCHEMBL31489351 | 0.82 | ROCK2 (0.35) | PIK3CGPIK3CDROCK2PIK3CA | |
| SCHEMBL31489910 | 0.81 | CYP11B2 (0.37) | MAPK1PIK3CGPIK3CDPDE10AKDM4E | |
| SCHEMBL31489906 | 0.75 | CREBBP (0.31) | — | |
| SCHEMBL31489311 | 0.75 | CREBBP (0.31) | — | |
| SCHEMBL31489179 | 0.71 | KDM4E (0.35) | MAPK1PDE10AKDM4EALDH1A1HTT | |
| SCHEMBL31489399 | 0.71 | KDM4E (0.35) | MAPK1PDE10AKDM4EALDH1A1HTT | |
| SCHEMBL25675424 | 0.69 | PIK3CG (0.52) | PIK3CGPIK3CDPAK4JAK1PIK3CA | |
| SCHEMBL25646778 | 0.69 | JAK2 (0.38) | PIK3CGPIK3CDROCK2PIM1PIM3 | |
| SCHEMBL31489689 | 0.67 | AHR (0.50) | MAPK1PDE10AROCK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |