Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 14/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489184 | 0.85 | PIK3CD (0.30) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489506 | 0.84 | ROCK2 (0.34) | ROCK2PIK3CAPIK3CG | |
| SCHEMBL31489207 | 0.82 | MAPK1 (0.33) | ROCK2PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489376 | 0.81 | TDP2 (0.32) | — | |
| SCHEMBL31489494 | 0.76 | NTRK1 (0.33) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489815 | 0.76 | SCN9A (0.34) | ROCK2 | |
| SCHEMBL31489702 | 0.76 | NTRK1 (0.33) | NTRK1PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489203 | 0.75 | PDE10A (0.32) | — | |
| SCHEMBL31489405 | 0.75 | PDE10A (0.34) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL31489399 | 0.69 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |