Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 15/20 | 0.34 |
| ▸ | TYK2 | P29597 | 9/20 | 0.34 |
| ▸ | JAK1 | P23458 | 8/20 | 0.34 |
| ▸ | JAK3 | P52333 | 7/20 | 0.34 |
| ▸ | FLT3 | P36888 | 10/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489235 | 0.90 | CCNE2 (0.33) | JAK2FLT3PTGDR2KDM4ESMN1; SMN2 | |
| SCHEMBL31489637 | 0.82 | MKNK1 (0.39) | JAK2TYK2JAK1JAK3MAPK1 | |
| SCHEMBL31489493 | 0.77 | CREBBP (0.32) | PTGDR2 | |
| SCHEMBL31489553 | 0.76 | CYP11B2 (0.40) | JAK2TYK2JAK1JAK3KDM4E | |
| SCHEMBL31489816 | 0.76 | CYP11B2 (0.40) | JAK2TYK2JAK1JAK3KDM4E | |
| SCHEMBL29425716 | 0.74 | JAK2 (0.47) | JAK2TYK2JAK1JAK3FLT3 | |
| SCHEMBL22852640 | 0.74 | JAK2 (0.47) | JAK2TYK2JAK1JAK3FLT3 | |
| SCHEMBL31489570 | 0.74 | MKNK1 (0.40) | JAK2TYK2JAK1JAK3MAPK1 | |
| SCHEMBL31489305 | 0.73 | MKNK1 (0.38) | JAK2TYK2JAK1JAK3KDM4E | |
| SCHEMBL31489373 | 0.73 | MKNK1 (0.38) | JAK2TYK2JAK1JAK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |