Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23761335 | 0.86 | JAK2 (0.41) | JAK2PDE10AADORA3ADORA2AADORA2B | |
| Trifluoroacetic Acid SCHEMBL31489607 | 0.84 | JAK2 (0.39) | JAK2MAPT | |
| SCHEMBL31489350 | 0.74 | JAK2 (0.41) | JAK2PDE10AADORA3ADORA2AADORA2B | |
| SCHEMBL31480915 | 0.67 | NUDT1 (0.49) | JAK2PDE10AADORA3ADORA2AADORA2B | |
| SCHEMBL31489346 | 0.67 | JAK2 (0.48) | JAK2NUDT1 | |
| Trifluoroacetic Acid SCHEMBL28218610 | 0.67 | NOS3 (0.43) | ALDH1A1CXCR4 | |
| SCHEMBL31423910 | 0.67 | JAK2 (0.41) | JAK2ALDH1A1MAPTADORA2ANUDT1 | |
| SCHEMBL1810011 | 0.65 | JAK2 (0.56) | JAK2PDE10AADORA3ADORA2AADORA2B | |
| SCHEMBL31489218 | 0.64 | KDM4E (0.40) | PDE10A | |
| SCHEMBL25385595 | 0.64 | JAK2 (0.39) | JAK2MAPTNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |