Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489394 | 0.94 | PDK2 (0.33) | PDK2 | |
| SCHEMBL31489310 | 0.83 | TDP2 (0.32) | PDK2JAK2JAK3PTK2TDP2 | |
| SCHEMBL31489191 | 0.82 | PDK2 (0.32) | PDK2JAK2JAK3PTK2 | |
| SCHEMBL31489413 | 0.81 | PIK3CG (0.38) | PDK2JAK2TDP2PIK3CAPIK3CG | |
| SCHEMBL31507742 | 0.81 | HSD17B14 (0.34) | TDP2PIK3CAPIK3CG | |
| SCHEMBL31489250 | 0.80 | PDK2 (0.35) | PDK2JAK2 | |
| SCHEMBL31489559 | 0.80 | SSTR4 (0.34) | TDP2 | |
| SCHEMBL31489497 | 0.79 | CREBBP (0.35) | JAK2 | |
| SCHEMBL31489502 | 0.79 | JAK2 (0.34) | PDK2JAK2 | |
| SCHEMBL31489529 | 0.78 | CREBBP (0.38) | JAK2TDP2PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |