Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 15/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489250 | 0.87 | PDK2 (0.35) | JAK2GPER1PDK2 | |
| SCHEMBL31489394 | 0.82 | PDK2 (0.33) | PDK2 | |
| SCHEMBL31489736 | 0.80 | CREBBP (0.38) | JAK2 | |
| SCHEMBL31489529 | 0.80 | CREBBP (0.38) | JAK2 | |
| SCHEMBL31489737 | 0.80 | RIPK1 (0.38) | JAK2PDK2ALOX5APFEN1 | |
| SCHEMBL31489509 | 0.80 | RIPK1 (0.38) | JAK2PDK2ALOX5APFEN1 | |
| SCHEMBL31489497 | 0.80 | CREBBP (0.35) | JAK2TBK1 | |
| SCHEMBL31489310 | 0.79 | TDP2 (0.32) | JAK2PDK2 | |
| SCHEMBL31507742 | 0.78 | HSD17B14 (0.34) | — | |
| SCHEMBL31489559 | 0.77 | SSTR4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |