Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147720 | 0.92 | CCR2 (0.52) | CCR2CACNA1BCACNA1HKCNH2HRH3 | |
| SCHEMBL3050672 | 0.86 | CCR2 (0.53) | CCR2KCNH2KDM4EALDH1A1PKM | |
| SCHEMBL3149815 | 0.86 | CCR2 (0.68) | CCR2KCNH2KDM4E | |
| SCHEMBL3149352 | 0.86 | CCR2 (0.65) | CCR2KCNH2ALDH1A1 | |
| SCHEMBL3153072 | 0.85 | CCR2 (0.50) | CCR2KCNH2KDM4EALDH1A1PKM | |
| SCHEMBL3145962 | 0.85 | CCR2 (0.51) | CCR2CACNA1BCACNA1HKCNH2HRH3 | |
| SCHEMBL3145968 | 0.85 | CCR2 (0.51) | CCR2CACNA1BCACNA1HKCNH2HRH3 | |
| SCHEMBL3148923 | 0.84 | L3MBTL3 (0.52) | CCR2KCNH2KDM4EALDH1A1PKM | |
| SCHEMBL3153707 | 0.83 | CCR2 (0.53) | CCR2CACNA1BCACNA1HKCNH2 | |
| SCHEMBL14430801 | 0.83 | EPHX2 (0.61) | CACNA1BCACNA1HHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-B1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-06-19 | — | — | EP | disclosed |
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075978-A1 | SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | BDKRB1, BDKRB2, TRPV1 | CCR2 417/4885CACNA1B 881/4885CACNA1H 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.