SCHEMBL3050672

SCHEMBL3050672

O=C(CNC(=O)c1ccc(S(=O)(=O)Nc2ccccc2Oc2ccccc2)cc1)NCCCN1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 9/20 0.53
BDKRB1 P46663 2/20 0.53
KCNH2 Q12809 1/20 0.53
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
POLB P06746 1/20 0.47
ACHE P22303 1/20 0.45
USP2 O75604 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3062074 0.94 CCR2 (0.57) CCR2KCNH2MEN1KMT2ASMN1; SMN2
SCHEMBL3049934 0.93 L3MBTL3 (0.49) CCR2BDKRB1KCNH2MEN1KMT2A
SCHEMBL3149352 0.89 CCR2 (0.65) CCR2KCNH2MEN1KMT2ASMN1; SMN2
SCHEMBL3054207 0.88 OPRM1 (0.49) ALDH1A1KDM4EPKM
SCHEMBL13834826 0.88 KMT2A (0.52) CCR2BDKRB1KCNH2MEN1KMT2A
SCHEMBL3059103 0.87 HSD17B10 (0.46) CCR2MEN1KMT2ASMN1; SMN2GAA
SCHEMBL3278520 0.87 CCR2 (0.49) CCR2BDKRB1KCNH2MEN1KMT2A
SCHEMBL3148923 0.87 L3MBTL3 (0.52) CCR2BDKRB1KCNH2MEN1KMT2A
SCHEMBL3148944 0.86 CCR2 (0.59) CCR2BDKRB1KCNH2ALDH1A1KDM4E
SCHEMBL3054853 0.86 POLB (0.52) CCR2MEN1KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8911547-B2 Decorative products and the production methods therefor COMPOCLAY HOLDINGS LIMITED (CN) 2014-12-16 US claimed
US-20120295910-A1 New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists BEKE GYULA (HU) 2012-11-22 US claimed
US-20120171429-A1 Novel Decorative Products and the Production Methods Therefor COMPOCLAY HOLDINGS LIMITED (HK) 2012-07-05 US claimed
US-20100221389-A1 Drinking Straw FRENKEN LEO GERARDUS 2010-09-02 US claimed
EP-0939920-B2 PLANOGRAPHIC PRINTING KODAK POLYCHROME GRAPHICS CO (US) 2008-07-23 EP claimed
EP-1915073-A2 DRINKING STRAW UNILEVER N.V. (NL) 2008-04-30 EP claimed
WO-2007019958-A2 DRINKING STRAW UNILEVER N.V. (NL) 2007-02-22 WO claimed
EP-0948578-B1 BIOMASS CONDITIONING UNIV LEEDS INNOVATIONS LTD (GB) 2002-12-04 EP claimed
US-6182571-B1 MAKING PRINTING MEMBER BY FORMING A HYDROPHILIC LAYER ON A SUPPORT BY CONTACTING WITH SOLUTION OF SPECIFIED ALKALI METAL SILICATE AND PARTICULATE, MODIFYING HYDROPHILIC LAYER WITH ALUMINUM SULFATE, ADDING IMAGE LAYER WITH INDICATOR KODAK POLCYHROME GRAPHICS LLC 2001-02-06 US claimed
EP-0948578-A1 BIOMASS CONDITIONING University of Leeds Innovations Ltd. (GB) 1999-10-13 EP claimed
WO-1998021292-A1 BIOMASS CONDITIONING UNIVERSITY OF LEEDS INNOVATIONS LIMITED (GB) 1998-05-22 WO claimed
EP-0590468-B1 Method of reducing residual monomers in the preparation of bead polymers ROEHM GMBH (DE) 1997-02-26 EP claimed
US-20220195263-A1 SYSTEM FOR PRODUCING A SEALING COMPOUND FOR INSULATING GLASS IGK Isolierglasklebstoffe GmbH (DE) 2022-06-23 US disclosed
EP-2943611-B1 FERROMAGNETIC FIBRE COMPOSITES BAE SYSTEMS PLC (GB) 2017-04-12 EP disclosed
US-20160136200-A1 GASTROINTESTINAL HEALTH, IMMUNITY AND PERFORMANCE BY DIETARY INTERVENTION BIOATLANTIS LTD (IE) 2016-05-19 US disclosed
US-9241951-B2 Of gastrointestinal health, immunity and performance by dietary intervention BIOATLANTIS LTD (IE) 2016-01-26 US disclosed
EP-0939920-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 1999-09-08 EP disclosed
WO-1998022853-A1 PLANOGRAPHIC PRINTING HORSELL GRAPHIC INDUSTRIES LIMITED (GB) 1998-05-28 WO disclosed
WO-1998021292-A1 BIOMASS CONDITIONING UNIVERSITY OF LEEDS INNOVATIONS LIMITED (GB) 1998-05-22 WO disclosed
US-5024703-A Reducing cereal storage proteins with ferrous sulfate, tin and copper chloride; air entrainment MULTISTRUCTURE SWEDEN AB (SE) 1991-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295910-A1 New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists BDKRB1, BDKRB2, HRH4 CCR2 390/4885BDKRB1 1/4885KCNH2 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.