Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489151 | 1.00 | ROCK2 (0.32) | ROCK2CYP17A1JAK2JAK1TYK2 | |
| SCHEMBL31489755 | 0.89 | ROCK2 (0.32) | ROCK2RIPK1 | |
| SCHEMBL31489898 | 0.87 | ROCK2 (0.32) | ROCK2CYP17A1MAPK1 | |
| SCHEMBL31489225 | 0.82 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL31489695 | 0.82 | TDP2 (0.31) | ROCK2RIPK1 | |
| SCHEMBL31489668 | 0.82 | TDP2 (0.31) | ROCK2RIPK1 | |
| SCHEMBL31489322 | 0.81 | ROCK2 (0.32) | ROCK2RIPK1 | |
| SCHEMBL31489564 | 0.81 | RIPK1 (0.33) | ROCK2RIPK1 | |
| SCHEMBL31489876 | 0.80 | PIK3CG (0.39) | ROCK2CYP17A1JAK2JAK1TYK2 | |
| SCHEMBL31489304 | 0.80 | PIK3CG (0.39) | ROCK2CYP17A1JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |