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Sugi Predict / Compounds / SCHEMBL31489755

SCHEMBL31489755

SCHEMBL31489755

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc2cc(-c3nc(-c4cnn(C(c5ccc(F)cc5)C(C)(F)F)c4)c(F)cc3F)ccn2n1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ROCK2 O75116 1/20 0.32
▸ RIPK1 Q13546 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489668 0.93 TDP2 (0.31) ROCK2RIPK1
SCHEMBL31489695 0.93 TDP2 (0.31) ROCK2RIPK1
SCHEMBL31489322 0.92 ROCK2 (0.32) ROCK2RIPK1
SCHEMBL31489564 0.92 RIPK1 (0.33) ROCK2RIPK1
SCHEMBL31489572 0.90 PIK3CG (0.34) ROCK2RIPK1
SCHEMBL31489636 0.89 ROCK2 (0.31) ROCK2RIPK1
SCHEMBL31489151 0.89 ROCK2 (0.32) ROCK2RIPK1
SCHEMBL31489416 0.89 RIPK1 (0.31) ROCK2RIPK1
SCHEMBL31489859 0.89 RIPK1 (0.31) ROCK2RIPK1
SCHEMBL31489670 0.89 ROCK2 (0.32) ROCK2RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 — — WO disclosed