Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474671 | 0.84 | MAPT (0.43) | CES2PTPN1CA1CA2MGLL | |
| SCHEMBL1350004 | 0.82 | LMNA (0.46) | KMT2ACES2CES1HSD11B1CA1 | |
| SCHEMBL7998701 | 0.79 | CES2 (0.52) | KMT2ACES2CES1HSD11B1PTPN1 | |
| SCHEMBL6588567 | 0.79 | KMT2A (0.47) | SLC6A3KMT2ACES2CES1HSD11B1 | |
| SCHEMBL31164032 | 0.72 | HSD11B1 (0.68) | HSD11B1POLBHTR2AHTR2CHTR7 | |
| SCHEMBL662115 | 0.72 | HSD11B1 (0.68) | HSD11B1POLBHTR2AHTR2CHTR7 | |
| SCHEMBL27996131 | 0.71 | NPC1 (0.43) | SLC6A3KMT2ACES2CES1HSD11B1 | |
| SCHEMBL14248417 | 0.71 | KMT2A (0.46) | SLC6A3KMT2AHSD11B1POLB | |
| SCHEMBL662218 | 0.69 | HSD11B1 (0.64) | HSD11B1POLBHTR2AHTR2CHTR7 | |
| SCHEMBL9420049 | 0.69 | CA1 (0.50) | KMT2ACES2CES1HSD11B1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |