Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489675 | 0.79 | SLC6A3 (0.47) | KMT2ASLC6A3CES2CES1HSD11B1 | |
| SCHEMBL14248417 | 0.73 | KMT2A (0.46) | KMT2ASLC6A3HSD11B1NPC1RAB9A | |
| SCHEMBL8442414 | 0.69 | KMT2A (0.34) | KMT2ASLC6A3CES2CES1HSD11B1 | |
| SCHEMBL662115 | 0.69 | HSD11B1 (0.68) | HSD11B1MGLLHTR7 | |
| SCHEMBL31164032 | 0.69 | HSD11B1 (0.68) | HSD11B1MGLLHTR7 | |
| SCHEMBL9887710 | 0.68 | POLB (0.76) | HSD11B1MGLLHTR7 | |
| SCHEMBL27996131 | 0.67 | NPC1 (0.43) | KMT2ASLC6A3CES2CES1HSD11B1 | |
| SCHEMBL1350004 | 0.67 | LMNA (0.46) | KMT2ACES2CES1HSD11B1MGLL | |
| SCHEMBL19762913 | 0.66 | NPC1 (0.53) | CES2CES1HSD11B1NPC1RAB9A | |
| SCHEMBL662218 | 0.66 | HSD11B1 (0.64) | HSD11B1MGLLHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |