⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913180 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL24283148 | 0.76 | — | — | |
| SCHEMBL23565132 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL24094076 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL23327679 | 0.64 | LMNA (0.35) | — | |
| SCHEMBL22290756 | 0.63 | LRRK2 (0.38) | — | |
| SCHEMBL21334010 | 0.63 | AR (0.31) | — | |
| SCHEMBL24745361 | 0.62 | LMNA (0.44) | — | |
| SCHEMBL9224907 | 0.60 | RIPK1 (0.32) | — | |
| SCHEMBL31227237 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028365-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC (US) | 2026-01-29 | — | — | US | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |