Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31493403 | 0.81 | AR (0.47) | KMT2AALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL1844382 | 0.79 | NPC1 (0.46) | KMT2AALDH1A1MAPK1CASP3POLB | |
| SCHEMBL6819794 | 0.75 | AR (0.45) | KMT2AALDH1A1CASP3POLBMEN1 | |
| SCHEMBL7607398 | 0.75 | LMNA (0.43) | KMT2AALDH1A1LMNAALOX15CYP1A2 | |
| SCHEMBL5121029 | 0.74 | RAB9A (0.49) | KMT2AALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL7474321 | 0.73 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL1417324 | 0.73 | LMNA (0.46) | KMT2AALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL16344633 | 0.72 | KMT2A (0.48) | KMT2AALDH1A1MAPK1TSHRLMNA | |
| SCHEMBL5118750 | 0.71 | ADORA3 (0.44) | ALDH1A1MAPK1TSHRLMNAHSD17B10 | |
| SCHEMBL25399863 | 0.70 | KMT2A (0.46) | KMT2AALDH1A1MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076236-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |