Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819794 | 0.87 | AR (0.45) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL20514935 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HTTKDM4ETDP1 | |
| SCHEMBL1844382 | 0.80 | NPC1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL31493403 | 0.79 | AR (0.47) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL32680245 | 0.74 | HSD17B10 (0.39) | ALDH1A1HSD17B10HCAR3GAAKMT2A | |
| SCHEMBL1841466 | 0.72 | SIGMAR1 (0.37) | SMN1; SMN2HTTTDP1TP53 | |
| SCHEMBL1662655 | 0.70 | AR (0.51) | ALDH1A1KMT2AMEN1TDP1TP53 | |
| Hydrochloric Acid SCHEMBL6151019 | 0.69 | AR (0.50) | ALDH1A1KMT2AMEN1TDP1TP53 | |
| SCHEMBL1844197 | 0.67 | TDP1 (0.38) | ALDH1A1HTTHCAR3GAAKMT2A | |
| SCHEMBL4703944 | 0.67 | HTT (0.40) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467969-B1 | DNA MINOR GROOVE BINDING COMPOUNDS | UNIV STRATHCLYDE (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-7700765-B2 | DNA minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20070117760-A1 | Dna minor groove binding compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117760-A1 | Dna minor groove binding compounds | PCNA, POLL, POLM | ALDH1A1 4824/4885SMN1; SMN2 4093/4885SIRT2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.