Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 4/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL617821 | 0.91 | PDK1 (0.45) | EPHA2PDK1KMT2AMEN1MMP13 | |
| SCHEMBL617822 | 0.91 | PDK1 (0.45) | EPHA2PDK1KMT2AMEN1MMP13 | |
| SCHEMBL618014 | 0.91 | PDK1 (0.45) | EPHA2PDK1KMT2AMEN1MMP13 | |
| SCHEMBL12527484 | 0.89 | KMT2A (0.43) | EPHA2PDK1KMT2AMEN1MMP13 | |
| SCHEMBL7291444 | 0.82 | STS (0.49) | EPHA2KMT2AMEN1GPR119ERBB2 | |
| SCHEMBL14835647 | 0.81 | EPHA2 (0.45) | EPHA2MMP13GPR119ERBB2EPHB4 | |
| SCHEMBL14835600 | 0.81 | EPHA2 (0.45) | EPHA2MMP13GPR119ERBB2EPHB4 | |
| SCHEMBL14835601 | 0.81 | EPHA2 (0.45) | EPHA2MMP13GPR119ERBB2EPHB4 | |
| SCHEMBL9214380 | 0.80 | ALDH1A1 (0.49) | EPHA2MMP13GPR119ERBB2EPHB4 | |
| SCHEMBL9216185 | 0.80 | ALDH1A1 (0.49) | EPHA2MMP13GPR119ERBB2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085815-A1 | PROTAC COMPOUNDS BINDING KEAP1 UBIQUITIN LIGASE FOR TARGETED PROTEIN DEGRADATION | SEED THERAPEUTICS US, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025083472-A2 | PROTAC COMPOUNDS BINDING KEAP1 UBIQUITIN LIGASE FOR TARGETED PROTEIN DEGRADATION | SEED THERAPEUTICS US, INC. (US) | 2025-04-24 | — | — | WO | disclosed |