SCHEMBL31495028

SCHEMBL31495028

Cc1ncccc1Nc1cc(Cl)ccc1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
HPGD P15428 4/20 0.41
GRM4 Q14833 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 1/20 0.41
HSD17B2 P37059 1/20 0.38
TNNI3K Q59H18 1/20 0.38
CCR9 P51686 1/20 0.37
NR4A2 P43354 2/20 0.37
PDE2A O00408 1/20 0.37
PDE10A Q9Y233 1/20 0.37
CYP3A4 P08684 3/20 0.37
KDM4E B2RXH2 2/20 0.36
TP53 P04637 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31495023 0.81 G6PD (0.39) ALDH1A1HPGDGRM4SMN1; SMN2RAB9A
SCHEMBL29581676 0.80 MAPT (0.50) ALDH1A1HPGDSMN1; SMN2RAB9AKDM4E
SCHEMBL31495035 0.80 HPGD (0.42) ALDH1A1HPGDGRM4SMN1; SMN2RAB9A
SCHEMBL145899 0.78 KMT2A (0.43) ALDH1A1RAB9AKDM4EMAPTMEN1
SCHEMBL31495042 0.77 NMT1 (0.43) SMN1; SMN2MEN1KMT2AMAPK10NPC1
SCHEMBL28231888 0.77 MAPT (0.50) ALDH1A1HPGDSMN1; SMN2RAB9ACYP3A4
SCHEMBL31495149 0.76 MAPT (0.50) ALDH1A1SMN1; SMN2CYP3A4MAPTMEN1
SCHEMBL4143510 0.76 KMT2A (0.41) ALDH1A1RAB9AKDM4EMAPTMEN1
SCHEMBL15227141 0.76 KMT2A (0.41) ALDH1A1RAB9AKDM4EMAPTMEN1
SCHEMBL30855342 0.76 KMT2A (0.41) ALDH1A1RAB9AKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025037871-A1 TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR 에스케이바이오팜 주식회사 2025-02-20 WO disclosed