Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.36 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495028 | 0.80 | ALDH1A1 (0.41) | HPGDALDH1A1SMN1; SMN2RAB9AGRM4 | |
| SCHEMBL29463915 | 0.77 | MAPT (0.49) | HPGDALDH1A1SMN1; SMN2RAB9AALOX15 | |
| SCHEMBL19463250 | 0.77 | MAPT (0.49) | HPGDALDH1A1SMN1; SMN2RAB9AALOX15 | |
| SCHEMBL31495071 | 0.76 | MAPT (0.51) | ALDH1A1SMN1; SMN2TSHRTDP1AHR | |
| SCHEMBL4926590 | 0.70 | MEN1 (0.55) | HPGDSMN1; SMN2RAB9AGAANPC1 | |
| SCHEMBL31495040 | 0.69 | GPR35 (0.48) | HPGDALDH1A1SMN1; SMN2RAB9ATDP1 | |
| SCHEMBL4930598 | 0.69 | CYP3A4 (0.48) | HPGDALDH1A1SMN1; SMN2RAB9AHSD17B2 | |
| SCHEMBL3075750 | 0.68 | CYP3A4 (0.52) | HPGDALDH1A1SMN1; SMN2HSD17B2CYP3A4 | |
| SCHEMBL29464137 | 0.68 | CYP3A4 (0.52) | HPGDALDH1A1SMN1; SMN2HSD17B2CYP3A4 | |
| SCHEMBL31495023 | 0.68 | G6PD (0.39) | HPGDALDH1A1SMN1; SMN2RAB9AGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |