Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.62 |
| ▸ | EP300 | Q09472 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22310321 | 0.85 | EP300 (0.53) | KDM1AEP300MAOBAKT1NOS3 | |
| SCHEMBL13449240 | 0.84 | MET (0.53) | KDM1AMAOB | |
| SCHEMBL31495102 | 0.84 | MET (0.53) | KDM1AMAOB | |
| SCHEMBL16787789 | 0.81 | SLC6A2 (0.61) | KDM1AEP300MAOBAKT1NOS3 | |
| Hydrochloric Acid SCHEMBL1474821 | 0.80 | SLC6A2 (0.60) | KDM1AEP300NOS3NOS1NOS2 | |
| SCHEMBL21322016 | 0.78 | EP300 (0.47) | KDM1AEP300MAOBAKT1NOS3 | |
| SCHEMBL13449241 | 0.75 | S1PR1 (0.47) | TDP1 | |
| SCHEMBL20772850 | 0.75 | HSD17B1 (0.45) | EP300 | |
| SCHEMBL12659969 | 0.74 | IKBKB (0.46) | KDM1AEP300MAOBAKT1TDP1 | |
| SCHEMBL30905863 | 0.74 | MET (0.55) | KDM1AEP300MAOBIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684263-A | Synthetic method of terpetinib and key intermediate thereof | 苏州莱安医药化学技术有限公司 | 2025-03-25 | — | — | CN | disclosed |