Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24715886 | 0.82 | NQO2 (0.47) | NQO2NSD2CASP6EGFRL3MBTL1 | |
| SCHEMBL4700757 | 0.78 | PDE4A (0.50) | NQO2EGFRL3MBTL1HPGDSALDH1A1 | |
| SCHEMBL2170435 | 0.75 | NQO2 (0.45) | NQO2EGFRALDH1A1CYP19A1 | |
| SCHEMBL5582304 | 0.74 | NQO2 (0.45) | NQO2KDR | |
| SCHEMBL2554129 | 0.72 | ALOX5AP (0.42) | NQO2NSD2CASP6EGFRPOLB | |
| SCHEMBL29855973 | 0.71 | KMT2A (0.54) | NQO2NSD2CASP6KDM4EUSP2 | |
| SCHEMBL621309 | 0.71 | KMT2A (0.54) | NQO2NSD2CASP6KDM4EUSP2 | |
| SCHEMBL435849 | 0.71 | HTR1A (0.44) | NSD2CASP6EGFRHPGDS | |
| SCHEMBL2134025 | 0.70 | HPGDS (0.60) | NQO2CASP6POLBHPGDSKDM4E | |
| SCHEMBL20918931 | 0.70 | CHRNB2 (0.46) | NSD2CASP6POLBL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279771-B | MAP4K1 inhibitors | 缆图药品公司 | 2025-03-21 | — | — | CN | disclosed |