Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 2/20 | 0.42 |
| ▸ | ATP4B | P51164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436008 | 0.81 | HTR1A (0.44) | HTR1AADRA1DADRA1AADRA1BHPGDS | |
| SCHEMBL437620 | 0.80 | ALOX5AP (0.38) | MCHR1 | |
| SCHEMBL442133 | 0.79 | BACE1 (0.41) | EGFR | |
| SCHEMBL441701 | 0.78 | ALDH1A1 (0.43) | HTR1AADRA1DADRA1AADRA1BTDP1 | |
| SCHEMBL439862 | 0.76 | HAVCR2 (0.63) | — | |
| SCHEMBL436963 | 0.75 | PDE5A (0.38) | NSD2CASP6EP300 | |
| SCHEMBL435823 | 0.75 | PARP1 (0.41) | CYP3A4 | |
| SCHEMBL441951 | 0.75 | HAVCR2 (0.58) | — | |
| SCHEMBL4014412 | 0.75 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BEGFR | |
| SCHEMBL30543156 | 0.75 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |