Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL932354 | 0.89 | POLB (0.43) | MEN1POLBKMT2ATDP1ALDH1A1 | |
| Bicarbonate SCHEMBL10762215 | 0.89 | POLB (0.43) | MEN1POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL28364774 | 0.89 | POLB (0.48) | MEN1POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL1057260 | 0.89 | — | — | |
| Bicarbonate SCHEMBL270124 | 0.86 | ALDH1A1 (0.46) | MEN1POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL148189 | 0.86 | MEN1 (0.46) | MEN1POLBKMT2AALDH1A1TSHR | |
| SCHEMBL7649857 | 0.86 | MEN1 (0.46) | MEN1POLBKMT2AALDH1A1TSHR | |
| SCHEMBL145456 | 0.86 | MEN1 (0.46) | MEN1POLBKMT2AALDH1A1TSHR | |
| Bicarbonate SCHEMBL347346 | 0.86 | ALDH1A1 (0.46) | MEN1POLBKMT2ATDP1ALDH1A1 | |
| SCHEMBL9719263 | 0.86 | MEN1 (0.46) | MEN1POLBKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119833722-A | Secondary battery and electricity utilization device | 合肥国轩高科动力能源有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119833722-A | Secondary battery and electricity utilization device | 合肥国轩高科动力能源有限公司 | 2025-04-15 | — | — | CN | disclosed |