SCHEMBL31496607

SCHEMBL31496607

Cn1c(=O)c(-c2nccc(N)n2)c(NC(CCO[Si](C)(C)C(C)(C)C)C(F)(F)F)n1COCC[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31530985 0.75 DGAT1 (0.36)
SCHEMBL25461534 0.65 NPC1 (0.34)
SCHEMBL18153384 0.59 DGAT1 (0.38)
SCHEMBL26616186 0.59 DGAT1 (0.32)
SCHEMBL30068004 0.56 CA12 (0.41) DUT
SCHEMBL30166560 0.56 DGAT1 (0.33)
SCHEMBL25407285 0.56 DGAT1 (0.33)
SCHEMBL23258151 0.56 DUT (0.41) DUT
SCHEMBL26428244 0.54 DGAT1 (0.36)
SCHEMBL31496552 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025036453-A1 EGFR MUTATION INHIBITORS AND USE THEREOF 上海和誉生物医药科技有限公司 2025-02-20 WO disclosed