Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25461534 | 0.77 | NPC1 (0.34) | DGAT1NPC1 | |
| SCHEMBL31496607 | 0.75 | DUT (0.31) | — | |
| SCHEMBL18153384 | 0.72 | DGAT1 (0.38) | DGAT1NPC1GRB2 | |
| SCHEMBL26616186 | 0.70 | DGAT1 (0.32) | DGAT1NPC1 | |
| SCHEMBL31531004 | 0.69 | DGAT1 (0.38) | DGAT1NPC1 | |
| SCHEMBL30166560 | 0.67 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL25407285 | 0.67 | DGAT1 (0.33) | DGAT1NPC1 | |
| SCHEMBL31530943 | 0.64 | NPC1 (0.34) | DGAT1NPC1 | |
| SCHEMBL28854726 | 0.64 | NCF1 (0.33) | NPC1 | |
| SCHEMBL31530956 | 0.63 | HTT (0.37) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912478-A | Amino heteroaryl macrocyclic compounds, preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-05-02 | — | — | CN | disclosed |