Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.55 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30752990 | 0.85 | PRMT5 (0.37) | PRMT5WDR77PARP1 | |
| SCHEMBL27002364 | 0.84 | PRMT5 (0.61) | PRMT5WDR77PARP1CYP1B1KMT2A | |
| SCHEMBL29915065 | 0.84 | PRMT5 (0.61) | PRMT5WDR77PARP1CYP1B1KMT2A | |
| SCHEMBL23087658 | 0.82 | PRMT5 (0.64) | PRMT5WDR77PARP1MAPTALDH1A1 | |
| SCHEMBL29735166 | 0.82 | PRMT5 (0.64) | PRMT5WDR77PARP1MAPTALDH1A1 | |
| SCHEMBL31496831 | 0.82 | PRMT5 (0.60) | PRMT5WDR77PARP1RAB9AMAPT | |
| SCHEMBL30752919 | 0.81 | PARP1 (0.32) | PARP1 | |
| SCHEMBL30752833 | 0.80 | PRMT5 (0.46) | PRMT5WDR77PARP1KMT2AMEN1 | |
| SCHEMBL31496822 | 0.78 | PRMT5 (0.53) | PRMT5WDR77PARP1RAB9AMAPT | |
| SCHEMBL30752949 | 0.78 | PRMT5 (0.53) | PRMT5WDR77PARP1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585261-A | PRMT5 inhibitor, preparation method and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-03-07 | — | — | CN | disclosed |