SCHEMBL31497326

SCHEMBL31497326

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nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CALCRL Q16602 4/20 0.46
▸ KEAP1 Q14145 3/20 0.46
▸ PRMT5 O14744 2/20 0.43
▸ WDR77 Q9BQA1 2/20 0.43
▸ RAMP3 O60896 4/20 0.42
▸ CALCR P30988 4/20 0.42
▸ CTSD P07339 1/20 0.42
▸ CTSE P14091 1/20 0.42
▸ CXCL8 P10145 3/20 0.40
▸ RAMP1 O60894 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31497341 0.92 CALCRL (0.52) CALCRLKEAP1PRMT5WDR77RAMP3
SCHEMBL31497321 0.91 KEAP1 (0.51) CALCRLKEAP1PRMT5WDR77
SCHEMBL31497325 0.90 CALCRL (0.52) CALCRLKEAP1PRMT5WDR77RAMP3
SCHEMBL31497348 0.90 CALCRL (0.50) CALCRLKEAP1PRMT5WDR77
SCHEMBL31497335 0.89 KEAP1 (0.55) CALCRLKEAP1PRMT5WDR77
SCHEMBL31497333 0.88 CALCRL (0.52) CALCRLKEAP1PRMT5WDR77RAMP3
SCHEMBL31497340 0.87 KEAP1 (0.54) CALCRLKEAP1PRMT5WDR77
SCHEMBL31497328 0.85 KEAP1 (0.52) CALCRLKEAP1PRMT5WDR77
SCHEMBL8176243 0.82 CXCL8 (0.59) CXCL8
SCHEMBL31497330 0.81 BACE1 (0.48) KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388623-A1 PEPTIDE INHIBITOR AND USE THEREOF CHENGDU BRILLIANT INSPIRATION BIOTHERAPEUTICS CO LTD (CN) 2025-12-25 — — US disclosed
EP-4545551-A1 PEPTIDE INHIBITOR AND USE THEREOF Chengdu Brilliant Inspiration Biotherapeutics Co., Ltd (CN) 2025-04-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388623-A1 PEPTIDE INHIBITOR AND USE THEREOF VIP, TGFB1, FN1 CALCRL 405/4885KEAP1 3525/4885PRMT5 2425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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