Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939502 | 0.83 | AHR (0.55) | AHRNR4A2F7LTA4HF3 | |
| Naphthoquinone SCHEMBL29182579 | 0.83 | MAPT (0.41) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL8666600 | 0.83 | HDAC1 (0.55) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL28091996 | 0.81 | HDAC1 (0.55) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL9913549 | 0.79 | NPC1 (0.44) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL17613377 | 0.79 | AHR (0.50) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL6963327 | 0.79 | AHR (0.50) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL951685 | 0.79 | USP2 (0.55) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL31543693 | 0.79 | AHR (0.55) | AHRNR4A2F7LTA4HF3 | |
| SCHEMBL763201 | 0.79 | AHR (0.50) | AHRNR4A2F7LTA4HF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471046-B | Carbazole indole quinone derivative and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2013071169-A1 | ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. (US) | 2013-05-16 | — | — | WO | disclosed |
| US-6833376-B2 | 5-aminoalkyl and 5-aminocarbonyl substituted indole derivative useful for treatment of psychosis in a mammal | H. LUNDBECK A/S (DK) | 2004-12-21 | — | — | US | disclosed |
| EP-1478643-A1 | 5-HETEROARYL SUBSTITUTED INDOLES | H. Lundbeck A/S (DK) | 2004-11-24 | — | — | EP | disclosed |
| EP-1214312-B1 | 5-AMINOALKYL AND 5-AMINOCARBONYL SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003070723-A1 | 5-HETEROARYL SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 2003-08-28 | — | — | WO | disclosed |
| US-6602889-B1 | 5-heteroaryl substituted indoles | H. LUNDBECK A.S. (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-1068198-B1 | 5-HETEROARYL SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 2003-05-28 | — | — | EP | disclosed |
| US-20020169169-A1 | 5-aminoalkyl and 5-aminocarbonyl substituted indoles | H. LUNDBECK A/S (DK) | 2002-11-14 | — | — | US | disclosed |
| EP-1214312-A1 | 5-AMINOALKYL AND 5-AMINOCARBONYL SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021614-A1 | 5-AMINOALKYL AND 5-AMINOCARBONYL SUBSTITUTED INDOLES | H. LUNDBECK A/S (DK) | 2001-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169169-A1 | 5-aminoalkyl and 5-aminocarbonyl substituted indoles | ADRB1, ADRA2C, ADRB2 | AHR 69/4885NR4A2 803/4885F7 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.