Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31497694 | 1.00 | ALDH1A1 (0.39) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| SCHEMBL794898 | 0.98 | ALDH1A1 (0.41) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| SCHEMBL29420741 | 0.98 | ALDH1A1 (0.41) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| SCHEMBL6232078 | 0.90 | ALDH1A1 (0.41) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| SCHEMBL19469378 | 0.85 | ESR1 (0.33) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL3287542 | 0.83 | HSD17B10 (0.34) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| Trifluoromethanesulfonic Acid SCHEMBL3287537 | 0.82 | PTGS1 (0.37) | ALDH1A1LMNAALOX15HTTHSD17B10 | |
| SCHEMBL3759525 | 0.80 | KMT2A (0.39) | ALDH1A1LMNAHTTHSD17B10CYP2C9 | |
| Hydrochloric Acid SCHEMBL4410534 | 0.78 | IDO1 (0.56) | LMNAALOX15HTTHSD17B10IDO1 | |
| Hydrochloric Acid SCHEMBL11157061 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAALOX15HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490444-A | Preparation method of photoacid generator (4, 7-dihydroxy-1-naphthyl) dimethyl sulfonium trifluoro methanesulfonate | 徐州博康信息化学品有限公司 | 2025-02-21 | — | — | CN | disclosed |