Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SI | P14410 | 4/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2715686 | 0.89 | LMNA (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL7031893 | 0.89 | CHRM2 (0.85) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL2716060 | 0.83 | CHRM2 (0.93) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499330 | 0.80 | LMNA (0.73) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL9342160 | 0.79 | LMNA (0.73) | LMNACHRM2ADORA3KCNH2MAPT | |
| Oxyphenisatine SCHEMBL239513 | 0.79 | CHRM2 (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| Oxyphenisatine SCHEMBL35387956 | 0.79 | CHRM2 (1.00) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL17813120 | 0.79 | MAPT (0.69) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499321 | 0.78 | LMNA (0.71) | LMNACHRM2ADORA3KCNH2MAPT | |
| SCHEMBL31499349 | 0.78 | LMNA (0.71) | LMNACHRM2ADORA3KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670798-B1 | COLOR AND HEAT STABLE POLYCARBONATE COMPOSITIONS AND METHODS OF MAKING | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-11-04 | — | — | EP | disclosed |