Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499347 | 1.00 | LMNA (0.54) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL2716061 | 0.82 | CYP19A1 (0.61) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL28614818 | 0.78 | BRD4 (0.54) | LMNAPDK2PDK4MEN1KMT2A | |
| SCHEMBL28217408 | 0.74 | BRD4 (0.58) | LMNAMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL2715686 | 0.71 | LMNA (1.00) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL31306897 | 0.68 | KMT2A (0.66) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL4548022 | 0.68 | LMNA (0.61) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL18552443 | 0.68 | KMT2A (0.66) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL6288766 | 0.68 | LMNA (0.61) | LMNAPDK2PDK4CHRM2ADORA3 | |
| SCHEMBL18197230 | 0.68 | LMNA (0.61) | LMNAPDK2PDK4CHRM2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954707-A | Chiral 3, 3-disubstituted indolone compound and preparation method and application thereof | 云南大学 | 2025-05-09 | — | — | CN | disclosed |