Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217408 | 0.87 | BRD4 (0.58) | BRD4LMNAMEN1POLBKMT2A | |
| SCHEMBL7484264 | 0.79 | MMP8 (0.59) | GRIN1GRIN2AGRIN2BMMP3MMP8 | |
| SCHEMBL31499347 | 0.78 | LMNA (0.54) | LMNAMEN1POLBKMT2AGAA | |
| SCHEMBL31499331 | 0.78 | LMNA (0.54) | LMNAMEN1POLBKMT2AGAA | |
| SCHEMBL26531017 | 0.73 | CYP19A1 (0.47) | LMNAGRIN1GRIN2AGRIN2BMEN1 | |
| SCHEMBL16204726 | 0.72 | BRD4 (1.00) | BRD4BRD2BRD3BRDT | |
| SCHEMBL2716061 | 0.71 | CYP19A1 (0.61) | BRD4LMNAMEN1POLBKMT2A | |
| SCHEMBL2715686 | 0.69 | LMNA (1.00) | LMNAMEN1POLBKMT2AGAA | |
| SCHEMBL6288766 | 0.66 | LMNA (0.61) | LMNAMEN1POLBKMT2AGAA | |
| SCHEMBL4548022 | 0.66 | LMNA (0.61) | LMNAMEN1POLBKMT2AMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440378-B | Preparation method of iodine-hydrogen peroxide promoted 3-amino-2-indolone derivative at room temperature | 宁波大学 | 2021-03-12 | — | — | CN | disclosed |