SCHEMBL3149936

SCHEMBL3149936

O=C(Oc1ccc(Cl)cc1)c1ccc(-c2ccc(C(=O)Oc3ccc(Cl)cc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.63
MEN1 O00255 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
HTT P42858 1/20 0.57
ALDH1A1 P00352 1/20 0.55
ALOX15 P16050 1/20 0.54
HSD17B10 Q99714 1/20 0.52
MAPT P10636 4/20 0.50
PARP10 Q53GL7 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
ELANE P08246 1/20 0.50
F2 P00734 1/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
HPGD P15428 1/20 0.48
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610755 0.94 KMT2A (0.69) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL9683516 0.94 KMT2A (0.69) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL10599787 0.94 KMT2A (0.69) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL28003430 0.94 KMT2A (0.69) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL7739094 0.93 PARP10 (0.57) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL3144272 0.91 KMT2A (0.56) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL1975085 0.86 KMT2A (0.61) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL10599791 0.86 ALOX15 (0.65) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL8718766 0.86 ALOX15 (0.65) KMT2AMEN1SMN1; SMN2HTTALDH1A1
SCHEMBL532864 0.86 KMT2A (0.61) KMT2AMEN1SMN1; SMN2HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041860-A1 POLYIMIDE, DIAMINE COMPOUND AND METHOD FOR PRODUCING THE SAME DDC, AOC1, DDT KMT2A 334/4885MEN1 360/4885SMN1; SMN2 2418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.