Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630514 | 0.81 | KIT (0.44) | IP6K1IP6K3IP6K2ALDH1A1CYP1A2 | |
| SCHEMBL25630777 | 0.81 | HRH4 (0.55) | EGFRALDH1A1HTTNPSR1LMNA | |
| SCHEMBL25725389 | 0.79 | ALDH1A1 (0.47) | EGFRALDH1A1CYP1A2CYP3A4CLK4 | |
| SCHEMBL25233084 | 0.78 | CYP1A2 (0.47) | EGFRIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL31501697 | 0.78 | CYP1A2 (0.47) | EGFRIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL25630734 | 0.75 | CYP1A2 (0.42) | EGFRIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL30405798 | 0.75 | OPRD1 (0.43) | ALDH1A1CYP1A2CYP3A4USP2CYP2C19 | |
| SCHEMBL25229495 | 0.74 | PDGFRB (0.39) | EGFRIP6K1IP6K3IP6K2ALDH1A1 | |
| SCHEMBL24010092 | 0.74 | ACHE (0.59) | ACHEBACE1AURKAMAPK1 | |
| SCHEMBL25272648 | 0.71 | KIT (0.49) | ALDH1A1CYP1A2CYP3A4USP2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |