Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684213 | 0.85 | PLA2G4B (0.69) | PLA2G4BLTB4RLTB4R2PTPN11TBXAS1 | |
| SCHEMBL31502436 | 0.84 | ALDH1A1 (0.47) | PLA2G4BMAOBALDH1A1LMNAMAOA | |
| SCHEMBL5266596 | 0.83 | PLA2G4B (0.56) | PLA2G4BLTB4RLTB4R2PTPN11TBXAS1 | |
| SCHEMBL19359554 | 0.81 | TP53 (0.64) | PLA2G4BALDH1A1 | |
| SCHEMBL8767652 | 0.80 | LTB4R (0.63) | PLA2G4BLTB4RLTB4R2LMNAFFAR1 | |
| SCHEMBL11683055 | 0.80 | PLA2G4B (0.61) | PLA2G4BLTB4RLTB4R2TBXAS1ALDH1A1 | |
| SCHEMBL11662474 | 0.80 | PLA2G4B (0.86) | PLA2G4BPTPN11ALDH1A1LMNACYP1A2 | |
| SCHEMBL6755448 | 0.80 | PLA2G4B (0.86) | PLA2G4BPTPN11ALDH1A1LMNACYP1A2 | |
| SCHEMBL9619291 | 0.80 | PLA2G4B (0.86) | PLA2G4BPTPN11ALDH1A1LMNACYP1A2 | |
| SCHEMBL7391119 | 0.80 | PLA2G4B (0.86) | PLA2G4BPTPN11ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127904-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | ADAXION THERAPEUTICS, INC. | 2025-04-24 | — | — | US | disclosed |
| WO-2025076427-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | OSPREY BIOPHARMACEUTICALS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127904-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | SIGLEC7, SIGLEC9, SELPLG | PLA2G4B 1740/4885LTB4R 391/4885LTB4R2 484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.