SCHEMBL31503141

SCHEMBL31503141

CC(C)=CC[SiH2]c1ccccc1[SiH2]CC=C(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.36
MAPT P10636 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
PKM P14618 2/20 0.33
KDM4E B2RXH2 2/20 0.33
PTGS1 P23219 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CDC25A P30304 1/20 0.33
CDC25B P30305 1/20 0.33
RPS6KA3 P51812 1/20 0.33
GLO1 Q04760 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GPR35 Q9HC97 1/20 0.33
ABCB11 O95342 1/20 0.33
LMNA P02545 1/20 0.33
COPS5 Q92905 1/20 0.33
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31503144 1.00 DHODH (0.36) DHODHMAPTMEN1KMT2APKM
SCHEMBL9501092 0.80 LMNA (0.36) DHODHMAPTMEN1KMT2APKM
SCHEMBL31503140 0.78 MAPT (0.36) DHODHMAPTMEN1KMT2APKM
SCHEMBL31503143 0.76
SCHEMBL31503142 0.74 XPO1 (0.33)
SCHEMBL25168630 0.70
SCHEMBL700561 0.67 ABCB11 (0.33) DHODHMAPTMEN1KMT2APKM
SCHEMBL9651773 0.66 ALDH1A1 (0.41) ALDH1A1HIF1ATSHR
SCHEMBL25168632 0.66 KMT2A (0.40) MEN1KMT2AKDM4EPTGS1ALDH1A1
SCHEMBL9651826 0.66 HTT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025039257-A1 A RESIN COMPOSITION WACKER CHEMIE AG (DE) 2025-02-27 WO disclosed