Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | GPR6 | P46095 | 2/20 | 0.49 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22495342 | 1.00 | MAPT (0.51) | MAPTPPARGGPR6PANK3ALDH1A1 | |
| SCHEMBL22495405 | 0.90 | MAPT (0.58) | MAPTGPR6ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL21771104 | 0.85 | RAB9A (0.62) | MAPTPANK3ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL31504260 | 0.84 | PANK3 (0.52) | MAPTPPARGGPR6PANK3ALDH1A1 | |
| SCHEMBL22495282 | 0.84 | PANK3 (0.52) | MAPTPPARGGPR6PANK3ALDH1A1 | |
| SCHEMBL31504183 | 0.83 | LMNA (0.54) | MAPTALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL22495244 | 0.83 | LMNA (0.54) | MAPTALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL22495190 | 0.82 | RAB9A (0.53) | MAPTPPARGPANK3ALDH1A1SMN1; SMN2 | |
| SCHEMBL22495214 | 0.79 | RAB9A (0.64) | MAPTPPARGPANK3ALDH1A1SMN1; SMN2 | |
| SCHEMBL30172115 | 0.79 | MAPT (0.54) | MAPTPPARGPANK3ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | claimed |