Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.65 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.65 |
| ▸ | PIM1 | P11309 | 3/20 | 0.65 |
| ▸ | PRKACA | P17612 | 3/20 | 0.65 |
| ▸ | GSK3B | P49841 | 3/20 | 0.65 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | CDK7 | P50613 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | PRKX | P51817 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443567 | 0.84 | CDC7 (0.52) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL12127498 | 0.82 | NUDT1 (0.61) | MAP4K4PRKACACLK4JAK3DYRK1B | |
| SCHEMBL18418494 | 0.80 | CDC7 (0.71) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL857180 | 0.76 | CDC7 (0.69) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL857887 | 0.76 | CDC7 (0.69) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL857471 | 0.76 | CDC7 (0.64) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL3740263 | 0.75 | CAMKK2 (0.69) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL17895432 | 0.73 | CDC7 (0.69) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL29484276 | 0.73 | CDC7 (0.69) | CDC7MAP4K4PIM1PRKACAGSK3B | |
| SCHEMBL4827398 | 0.73 | CDC7 (0.53) | CDC7MAP4K4PIM1PRKACAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |