Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 5/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | WNT1 | P04628 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684326 | 1.00 | CHEK1 (0.44) | CHEK1CHEK2LMNAMYCLRRK2 | |
| SCHEMBL31507488 | 0.73 | LMNA (0.42) | LMNASIRT6GSK3BGRM2 | |
| SCHEMBL26684723 | 0.73 | LMNA (0.42) | LMNASIRT6GSK3BGRM2 | |
| SCHEMBL1786530 | 0.72 | CD38 (0.50) | CHEK1CHEK2LMNAMYCLRRK2 | |
| SCHEMBL31173737 | 0.69 | CHEK2 (0.67) | CHEK1CHEK2MYCCD38MKNK1 | |
| SCHEMBL20338978 | 0.69 | ALDH1A1 (0.60) | CHEK1CHEK2MYCLRRK2 | |
| SCHEMBL11616643 | 0.68 | LMNA (0.59) | LMNASIRT6GRM2 | |
| SCHEMBL30097621 | 0.68 | LMNA (0.59) | LMNASIRT6GRM2 | |
| SCHEMBL30929137 | 0.67 | CHEK1 (0.56) | CHEK1CHEK2MYCLRRK2CD38 | |
| SCHEMBL1685078 | 0.67 | CHEK1 (0.56) | CHEK1CHEK2MYCLRRK2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119546602-A | Pyrrolidone derivatives as inhibitors of nfkb-induced kinase | 詹森药业有限公司 | 2025-02-28 | — | — | CN | disclosed |