Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514565 | 0.90 | CNR2 (0.54) | CNR2TDO2MAP4K4EGFRAURKB | |
| SCHEMBL31514609 | 0.89 | HTR2A (0.50) | CNR2TDO2MAP4K4RAF1BRAF | |
| SCHEMBL31514563 | 0.88 | EGFR (0.51) | TDO2MAP4K4RAF1BRAFEGFR | |
| SCHEMBL31514581 | 0.87 | EGFR (0.54) | CNR2MAP4K4EGFRAURKAKIT | |
| SCHEMBL31514625 | 0.85 | TDO2 (0.48) | CNR2TDO2MAP4K4RAF1BRAF | |
| SCHEMBL31514592 | 0.85 | TDO2 (0.48) | CNR2TDO2MAP4K4ERN1EGFR | |
| SCHEMBL31514567 | 0.85 | EGFR (0.49) | CNR2ERBB2TDO2MAP4K4EGFR | |
| SCHEMBL31514559 | 0.85 | MAP4K4 (0.51) | CNR2TDO2MAP4K4EGFRKIT | |
| SCHEMBL31514586 | 0.84 | EGFR (0.48) | TDO2MAP4K4RAF1BRAFEGFR | |
| SCHEMBL31514587 | 0.83 | EGFR (0.54) | CNR2CDK2MAP4K4EGFRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |