Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31521301 | 0.82 | PRCP (0.40) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL1899568 | 0.79 | — | — | |
| SCHEMBL29080159 | 0.75 | PNMT (0.31) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL11921322 | 0.75 | SLC6A1 (0.30) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL24050612 | 0.70 | KMT2A (0.39) | GABRA5GABRB2GABRA1GABRA4 | |
| SCHEMBL5230146 | 0.70 | PLG (0.33) | — | |
| SCHEMBL10430855 | 0.69 | CHRNB2 (0.33) | HTR2C | |
| SCHEMBL10431005 | 0.69 | CA1 (0.30) | — | |
| SCHEMBL30790418 | 0.69 | — | — | |
| SCHEMBL30790567 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790059-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物股份有限公司 | 2025-04-08 | — | — | CN | disclosed |