Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744226 | 0.81 | PDE2A (0.44) | PDE2ALMNAKCNH2ADRB1ADRA2A | |
| SCHEMBL954835 | 0.81 | CES2 (0.47) | PDE2ALMNAADRB1ADRA2AADRB3 | |
| SCHEMBL16070801 | 0.81 | CYP2D6 (0.52) | LMNAKCNH2ADRB1AOC3ADRB2 | |
| SCHEMBL29669152 | 0.80 | PDE2A (0.53) | PDE2ALMNAKCNH2TP53CES2 | |
| SCHEMBL7983483 | 0.80 | PDE2A (0.53) | PDE2ALMNAKCNH2TP53CES2 | |
| SCHEMBL20237842 | 0.80 | PDE2A (0.53) | PDE2ALMNAKCNH2TP53CES2 | |
| SCHEMBL22871213 | 0.79 | TSHR (0.47) | LMNATSHR | |
| SCHEMBL27918656 | 0.79 | CYP3A4 (0.39) | PDE2ALMNAKCNH2ADRB1CES2 | |
| SCHEMBL31521446 | 0.78 | CFD (0.41) | LMNA | |
| SCHEMBL15915397 | 0.78 | CFD (0.47) | PDE2ALMNAKCNH2ADRB1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096957-A1 | RAS-PI3K INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |