Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 4/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20237842 | 1.00 | PDE2A (0.53) | PDE2ALMNACES2CES1CYP3A4 | |
| SCHEMBL7983483 | 1.00 | PDE2A (0.53) | PDE2ALMNACES2CES1CYP3A4 | |
| SCHEMBL5107133 | 0.84 | LMNA (0.61) | PDE2ALMNATSHRCYP2D6 | |
| SCHEMBL5107136 | 0.84 | LMNA (0.61) | PDE2ALMNATSHRCYP2D6 | |
| SCHEMBL30172716 | 0.84 | LMNA (0.61) | PDE2ALMNATSHRCYP2D6 | |
| SCHEMBL5107130 | 0.84 | LMNA (0.61) | PDE2ALMNATSHRCYP2D6 | |
| SCHEMBL954835 | 0.83 | CES2 (0.47) | PDE2ALMNACES2CES1CYP3A4 | |
| SCHEMBL1913425 | 0.83 | CES2 (0.42) | PDE2ALMNACES2CES1CYP3A4 | |
| SCHEMBL6630352 | 0.82 | ALDH1A1 (0.42) | PDE2ALMNACES2CES1CYP3A4 | |
| SCHEMBL31521269 | 0.80 | PDE2A (0.44) | PDE2ALMNACES2CES1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325531-B | Benzenesulfonamides and their use as therapeutic agents | 泽农医药公司 | 2022-05-27 | — | — | CN | disclosed |