Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KCNJ6 | P48051 | 14/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 14/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 9/20 | 0.51 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011586 | 0.81 | RAB9A (0.88) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL22896928 | 0.80 | ALDH1A1 (0.55) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL28330785 | 0.79 | NPC1 (0.56) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL19377699 | 0.77 | KEAP1 (0.52) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL4513114 | 0.77 | KCNJ6 (0.72) | KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL17580180 | 0.77 | KCNJ6 (0.55) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL1013974 | 0.75 | RAB9A (0.94) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL15727520 | 0.75 | RAB9A (1.00) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL23203519 | 0.75 | KCNJ6 (0.65) | NPC1LMNATP53PKMRAB9A | |
| SCHEMBL30672491 | 0.75 | NPC1 (0.51) | NPC1LMNATP53PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058611-A | 1-Aryl-5-pyrazolone compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-119930520-A | N-aryl pyrazole compound, and pharmaceutical composition and application thereof | 中国药科大学 | 2025-05-06 | — | — | CN | disclosed |