SCHEMBL31522467

SCHEMBL31522467

OCc1c(Cl)cc(B(O)O)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 4/20 0.47
ENPP2 Q13822 3/20 0.39
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
EGFR P00533 1/20 0.32
LMNA P02545 1/20 0.32
ESR1 P03372 1/20 0.32
ERBB2 P04626 1/20 0.32
CYP1A2 P05177 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
PGR P06401 1/20 0.32
POLB P06746 1/20 0.32
HSP90AA1 P07900 1/20 0.32
CYP3A4 P08684 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
HSPA1A P0DMV8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320021 0.74 TSHR (0.48) TTRMEN1EGFRLMNAESR1
SCHEMBL4912906 0.74 TTR (0.48) TTRMEN1NPC1USP2EGFR
SCHEMBL2521376 0.74 TTR (0.48) TTRENPP2MEN1NPC1USP2
SCHEMBL5940300 0.72 HSD17B10 (0.52) TTRMEN1NPC1USP2EGFR
SCHEMBL522619 0.72 ACHE (0.43) TTRMEN1NPC1USP2EGFR
SCHEMBL20286649 0.72 HSD17B10 (0.52) TTRENPP2MEN1NPC1USP2
SCHEMBL4469629 0.71 ENPP2 (0.39) ENPP2
SCHEMBL16687418 0.71 ENPP2 (0.39) ENPP2
SCHEMBL17236432 0.71 TTR (0.52) TTRENPP2TSHR
SCHEMBL25370371 0.70 IDO1 (0.33) MEN1NPC1USP2EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025053379-A1 NOVEL COMPOUND AND USE THEREOF FOR TREATING PSORIASIS 광주과학기술원 2025-03-13 WO disclosed