SCHEMBL31570705

SCHEMBL31570705

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(Cc3ccc4ccccc4c3)c3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GNMT Q14749 1/20 0.39
▸ PRMT5 O14744 15/20 0.34
▸ METTL3 Q86U44 13/20 0.34
▸ PRMT9 Q6P2P2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526195 0.90 ADK (0.39) GNMTPRMT5METTL3
SCHEMBL31526115 0.88 GNMT (0.33) GNMT
SCHEMBL31526151 0.87 PRMT5 (0.35) PRMT5PRMT9
SCHEMBL31526252 0.87 GNMT (0.54) GNMTPRMT5METTL3PRMT9
SCHEMBL31526088 0.87 ADK (0.36) GNMTPRMT5METTL3PRMT9
SCHEMBL31526204 0.86 PRMT5 (0.35) PRMT5PRMT9
SCHEMBL31526181 0.86 ADK (0.41) PRMT5PRMT9
SCHEMBL31526254 0.85 PRMT5 (0.41) PRMT5METTL3PRMT9
SCHEMBL31526395 0.85 PRMT5 (0.35) GNMTPRMT5METTL3PRMT9
SCHEMBL31526211 0.85 DOT1L (0.33) PRMT5PRMT9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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