Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | METAP1 | P53582 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352678 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL955714 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL15692161 | 0.79 | MAPK1 (0.56) | LMNAKDM4EMETAP1CYP3A4RXFP1 | |
| SCHEMBL25522278 | 0.79 | ACACA (0.72) | LMNAHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL8140217 | 0.77 | ADORA2A (0.50) | SMN1; SMN2LMNAHPGDKDM4EALDH1A1 | |
| SCHEMBL13243235 | 0.76 | CYP3A4 (0.53) | KDM4EALDH1A1MAPTMETAP1CYP3A4 | |
| SCHEMBL25416501 | 0.76 | KDM4E (0.61) | LMNAKDM4EMETAP1CYP3A4RXFP1 | |
| SCHEMBL30368831 | 0.76 | ACHE (0.64) | LMNAKDM4EMETAP1CYP3A4RXFP1 | |
| SCHEMBL10610977 | 0.76 | KDM4E (0.57) | SMN1; SMN2LMNAKDM4EALDH1A1METAP1 | |
| SCHEMBL2712210 | 0.76 | ACHE (0.64) | LMNAKDM4EMETAP1CYP3A4RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | IGF1R, IGFBP1, IGFBP2 | SMN1; SMN2 1317/4885LMNA 978/4885HPGD 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.