Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.56 |
| ▸ | KDR | P35968 | 12/20 | 0.52 |
| ▸ | FLT1 | P17948 | 6/20 | 0.52 |
| ▸ | TEK | Q02763 | 6/20 | 0.52 |
| ▸ | KIT | P10721 | 5/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.52 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | LYN | P07948 | 2/20 | 0.52 |
| ▸ | RET | P07949 | 2/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.52 |
| ▸ | FLT4 | P35916 | 2/20 | 0.52 |
| ▸ | FRK | P42685 | 2/20 | 0.52 |
| ▸ | SYK | P43405 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31531262 | 0.83 | FLT3 (0.57) | FLT3KDRFLT1TEKKIT | |
| SCHEMBL11149 | 0.81 | BTK (0.51) | KDRRIPK1 | |
| SCHEMBL21467072 | 0.79 | TRPA1 (0.41) | FGFR1 | |
| SCHEMBL31531270 | 0.75 | FLT3 (0.59) | FLT3KDRFLT1KITROCK2 | |
| SCHEMBL3836444 | 0.75 | FLT3 (0.49) | FLT3KDRFLT1TEKKIT | |
| Trifluoroacetic Acid SCHEMBL29836326 | 0.74 | NUDT14 (0.52) | KDRTEKLCKLYNBLK | |
| SCHEMBL20793915 | 0.73 | TTK (0.47) | FLT3KDRFLT1TEKKIT | |
| SCHEMBL4865620 | 0.73 | PTK2 (0.54) | FLT3KDRAURKBAURKAPTK2 | |
| SCHEMBL31531241 | 0.72 | KIT (0.85) | FLT3KDRFLT1KITLCK | |
| SCHEMBL17229949 | 0.72 | FLT3 (1.00) | FLT3KDRKITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |