Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | STK4 | Q13043 | 3/20 | 0.42 |
| ▸ | STK3 | Q13188 | 3/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352960 | 0.82 | LRRK2 (0.58) | FLT3RIPK2LRRK2RETSTK4 | |
| SCHEMBL4353306 | 0.80 | LRRK2 (0.62) | RIPK2LRRK2STK4STK3MAP4K4 | |
| SCHEMBL8107167 | 0.79 | FLT3 (0.46) | FLT3LRRK2RETSTK4STK3 | |
| SCHEMBL24710755 | 0.79 | LRRK2 (0.51) | FLT3LRRK2RETSTK4STK3 | |
| SCHEMBL1896766 | 0.76 | STK3 (0.58) | FLT3RIPK2LRRK2RETSTK4 | |
| SCHEMBL3787081 | 0.76 | SRC (0.50) | FLT3LRRK2RETSTK4STK3 | |
| SCHEMBL23917432 | 0.76 | LRRK2 (0.50) | FLT3RIPK2LRRK2RETSTK3 | |
| SCHEMBL8107173 | 0.75 | FLT3 (0.46) | FLT3LRRK2RETSTK4STK3 | |
| SCHEMBL7021288 | 0.75 | LRRK2 (0.63) | FLT3LRRK2RETSTK4STK3 | |
| SCHEMBL30717977 | 0.75 | TRPA1 (0.45) | FLT3LRRK2STK4STK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |