Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.64 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.62 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28581917 | 0.98 | CRHBP (0.62) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL27537075 | 0.84 | CRHBP (0.60) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL3146890 | 0.83 | KCNH2 (0.62) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| Hydrochloric Acid SCHEMBL9151033 | 0.83 | MAPK1 (0.59) | CRHBPCRHR2PYCR1HRH3ACHE | |
| SCHEMBL15392240 | 0.83 | LOXL2 (0.59) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL3154646 | 0.82 | PYCR1 (0.66) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL3143221 | 0.81 | CRHBP (0.71) | CRHBPCRHR2PYCR1KCNH2ACHE | |
| SCHEMBL4810294 | 0.81 | CRHBP (0.61) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL3148248 | 0.81 | ACHE (0.64) | CRHBPCRHR2PYCR1LOXL2KCNH2 | |
| SCHEMBL3152144 | 0.81 | KCNH2 (0.68) | CRHBPCRHR2PYCR1LOXL2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119680367-A | Dioxin inhibitor for mixed combustion of municipal sludge and household garbage and preparation method thereof | 河南省化工研究所有限责任公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119680367-A | Dioxin inhibitor for mixed combustion of municipal sludge and household garbage and preparation method thereof | 河南省化工研究所有限责任公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119680367-A | Dioxin inhibitor for mixed combustion of municipal sludge and household garbage and preparation method thereof | 河南省化工研究所有限责任公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-117255734-A | Polymer composition comprising polypropylene and hydrocarbon resin | 博里利斯股份公司 | 2023-12-19 | — | — | CN | disclosed |
| WO-2023237759-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR | ANAGENESIS BIOTECHNOLOGIES (FR) | 2023-12-14 | — | — | WO | disclosed |
| EP-4289427-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR. | Anagenesis Biotechnologies (FR) | 2023-12-13 | — | — | EP | disclosed |
| CN-108715589-B | Coumarin derivative used as caspase-3 activator and application thereof | 华侨大学 | 2021-04-20 | — | — | CN | disclosed |
| US-10294260-B2 | Tetracyclic anthraquinone derivatives | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD. (CN) | 2019-05-21 | — | — | US | disclosed |
| CN-109265453-A | It is a kind of as the semicarbazones analog derivative of caspase-3 activator and its application | 华侨大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-108715589-A | A kind of coumarin derivatives and its application as caspase-3 activator | 华侨大学 | 2018-10-30 | — | — | CN | disclosed |
| WO-1999062882-A1 | SUBSTITUTED INDOLINONES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-12-09 | — | — | WO | disclosed |
| WO-1999032100-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999032468-A1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |
| CN-1043766-C | Indole derivative and preparation and pharmaceutical using of same | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| US-5852030-A | Indole derivatives, process for producing the same and medicinal uses of the same | TORAY INDUSTRIES, INC. (JP) | 1998-12-22 | — | — | US | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |
| EP-0614898-A1 | INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |
| US-4193800-A | COLOR DIFFUSION TRANSFER, POLYMER HAVING ACRYLOLAMINOPHENYL AMMONIUM UNITS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-03-18 | — | — | US | disclosed |
| US-4147548-A | Photographic element comprising quaternary nitrogen polymeric mordant | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294260-B2 | Tetracyclic anthraquinone derivatives | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, F12, ANTXR2 | CRHBP 4758/4885CRHR2 3606/4885PYCR1 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.